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Description
SDF-1β/CXCL12 Protein, HumanProduct Specification Species Human Synonyms Stromal cell derived factor 1; SDF 1; hSDF 1; C X C motif chemokine 12; Intercrine reduced in hepatomas (IRH hIRH); Pre B cell growth stimulating factor (PBSF); Accession P48061 Amino Acid Sequence Lys22 Met93 Expression System E. coli Molecular Weight 10 kDa (Reducing) Purity >95% by SDS PAGE. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer PBS,
Product Specification
| Species | Human |
| Synonyms | Stromal cell-derived factor 1; SDF-1; hSDF-1; C-X-C motif chemokine 12; Intercrine reduced in hepatomas (IRH hIRH); Pre-B cell growth-stimulating factor (PBSF); |
| Accession | P48061 |
| Amino Acid Sequence | Lys22-Met93 |
| Expression System | E.coli |
| Molecular Weight | 10 kDa (Reducing) |
| Purity | >95% by SDS-PAGE. |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.0 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | Nature. 2001 Mar 1;410(6824):50-6. |
Background
Stromal Cell-Derived Factor 1 beta (SDF-1β), also known as CXCL12, is a chemokine protein that plays a crucial role in immune cell trafficking, hematopoiesis, and tissue repair. SDF-1β is produced by stromal cells, endothelial cells, and fibroblasts, and acts as a chemoattractant for a variety of immune cells, including lymphocytes, monocytes, and hematopoietic stem cells. SDF-1β binds to its receptor, CXCR4, and regulates cell migration, adhesion, and survival. This chemokine is involved in various physiological and pathological processes, such as inflammation, angiogenesis, and cancer metastasis.
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