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Description
FITC Rat Anti-Mouse CD2 Antibody (S-R721)Product Specification Host Rat Antigen CD2 Synonyms T cell surface antigen CD2; LFA 2; LFA 3 receptor; Lymphocyte antigen 37 (Ly 37); T cell surface antigen T11 Leu 5; Ly 37 Location Cell membrane Accession P08920 Clone Number S R721 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS,
Product Specification
| Host | Rat |
| Antigen | CD2 |
| Synonyms | T-cell surface antigen CD2; LFA-2; LFA-3 receptor; Lymphocyte antigen 37 (Ly-37); T-cell surface antigen T11/Leu-5; Ly-37 |
| Location | Cell membrane |
| Accession | P08920 |
| Clone Number | S-R721 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | BALB/c mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | FITC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD2, also known as the T-cell rosette receptor or LFA-2, is a type I membrane protein predominantly expressed on thymocytes and mature T cells. It functions as an adhesion molecule that binds to CD58 (LFA-3) on antigen-presenting cells (APCs), facilitating T-cell receptor (TCR) binding and signal transduction, which is crucial for T-cell activation and immune responses.
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Exchange/Return Notes
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