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The first phase 3 retatrutide trial, TRIUMPH 4, top line data announced today Retatrutide, a triple GLP 1,GIP, glucagon agonist studied in patients with obesity and osteoarthritis 28.7% weight loss at 68 michigan semaglutide vomiting class action Glucagon Like Peptide 1 (GLP 1) Agonists: Decreasing Waistlines, Increasing Poison Center Cases Balancing weight and muscle loss in GLP1 receptor agonist therapy Nature Reviews Endocrinology Retatrutide Phase 1 Peptides GLP 1 receptor agonists How Wegovy, Ozempic, and Mounjaro work How Many Calories Should You Eat on GLP 1 Medications? Fella Health
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4.6 ★★★★★
Based on 697 reviews
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Product Reviews
★★★★★ 3
Run small
Size: 3X-Large
I even went up a size and they were still quite uncomfortable due to being too small. They just plain didn’t fit so you might wanna go up a couple of sizes
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Reviewed in the United States on December 28, 2025
★★★★★ 5
Who knew!?
Size: 3X-Large
I have problems with elastic around my legs so I looked for underwear without the elastic and found these. Okay, not the best look for “date night” but the itchiness is gone when I wear these underwear. I consider it a miracle! Date night will just have to be à la cart.
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Reviewed in the United States on May 14, 2026
★★★★★ 4
Lil tight
Size: 3X-Large
Def purchase a size above what you normally wear. I unfortunately could not go any higher of a size. Its more of a snug fit, somewhat stretchy, but the fabric is soft and feels great. If the size was just a lil bit bigger these would be perfect. But they feel good.
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Reviewed in the United States on April 25, 2026
★★★★★ 5
Love
Size: Medium
I am someone that really does not like to wear underwear, but I don't need to be flashing everybody. I probably should have went with some calmer prints, but they are comfy! Sometimes I forget that they are supposed to be underwear and I walk outside in them.
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Reviewed in the United States on April 22, 2026
★★★★★ 2
Size chart does not reflect actual size of garment.
Size: 3X-Large
I ordered these according to the size chart. Asian sizes are much different from U.S. sizes. What I received does not coincide with measurements given. The only good thing I can say is that the colors are pretty.
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Reviewed in the United States on January 7, 2026