Mouse Anti-Human CD200R Antibody (S-3128)
SKU: 30052384320

Mouse Anti-Human CD200R Antibody (S-3128)

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Description

Mouse Anti-Human CD200R Antibody (S-3128)Product Specification Host Mouse Antigen CD200R Synonyms Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CRTR2; MOX2R; OX2R; CD200R1 Location Cell membrane Accession Q8TD46 Clone Number S 3128 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample human peripheral blood Leukocyte Purification Protein G Concentration 2 mg ml Conjugation

Product Specification


Host Mouse
Antigen CD200R
Synonyms Cell surface glycoprotein CD200 receptor 1; CD200 cell surface glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CRTR2; MOX2R; OX2R; CD200R1
Location Cell membrane
Accession Q8TD46
Clone Number S-3128
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Positive Sample human peripheral blood Leukocyte
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1:200 Hu

Background

CD200R is a trans-membrane glycoprotein of the immunoglobulin superfamily encoded by CD200R1, expressed chiefly on myeloid cells (macrophages, dendritic cells, microglia) and some lymphoid subsets; when engaged by its ligand CD200 (OX-2) it becomes tyrosine-phosphorylated in its cytoplasmic NPxY motif, recruits the adaptor Dok-2 and RasGAP, thereby dampening Ras/MAPK and NF-κB signaling to suppress production of TNF-α, interferons and iNOS, curb mast-cell degranulation, restrain ILC2 effector cytokines, and broadly down-regulate innate and adaptive inflammatory responses, a signaling axis that is exploited by tumors for immune evasion and is being therapeutically targeted to treat asthma, neuroinflammation and cancer .

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Exchange/Return Notes
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SKU: 30052384320

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4.7 ★★★★★
Based on 1195 reviews
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Product Reviews
B
Verified Purchase
billy
Grantham, US
★★★★★ 5
My dog is a toy destroyer
Color: Consuela the Cactus - Large, Size: Large Dog, Color: Consuela the Cactus - Large, Size: Large Dog
I’ve had a hard time trying to find toys that my dog, Zara loves because she’s actually very picky. Ive gotten plenty of Kong toys that are well known to be indestructible but she wants nothing to do with them. Then I got her ropes and that seemed to be good for a while until she was getting sick in the middle of the night from eating all of the string. Stuffed toys aren’t good because she’ll rip them within seconds and eat all of the stuffing. I felt like I’ll never score the perfect toy for her. I found the three layered cactus toy and decided to give it a go. It’s clearly designed to be ripped and destroyed to get the ball in the middle which is actually really cute and fun to see all of the layers. The cactus arms have stuffing and of course that’s the first thing she went for and ate. I had to watch her and make sure I took the stuffing away before she ate it. And before I knew it, she ate half of the first layer fabric lol once she got through the first layer, all she’s been doing is walking around the house with the toy in her mouth. But now she’s tired and passed out on the couch from all of the fun. This toy won’t last long with a toy destroyer but it sure does give them something to do and it’s a cute toy. I do recommend!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 26, 2024
K
Verified Purchase
Klara Gengler
Phoenix, US
★★★★★ 5
Last a while. Will be buying more toys soon.
Color: Consuela the Cactus - Large, Size: Large Dog
Best dog toy I have ever bought. I have three dogs, two at the time I bought this toy. It took them over a year to break through the first layer. The flower comes off first so be careful your dog doesn't swallow it. It still has the second layer so it still looks like a cactus. No stuffing to clean up when they tear into it, which makes it far less messy than other toys. One of my dogs is obsessed with fetch so I use it like a ball inside. The oval shape makes it hard to ensure when it bounces that it will bounce straight. It's bounced into walls and other stuff that I wasn't intending it to hit. Not much of a squeak so I can let them play with it for hours and I don't get annoyed with the noise. Great toy that lasts a while.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 25, 2025
C
Verified Purchase
Cassie
Houston, US
★★★★★ 5
Nice Value
Color: Consuela the Cactus - Large, Size: Large Dog
Very cute! Its soft and feels like it is well made. It is a heavier toy and a tougher one. Not a plush toy. I will order again for our older dogs. Nice value for sure!
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Reviewed in the United States on June 11, 2026
B
Verified Purchase
Blakely McAllister
Louisville, US
★★★★★ 5
Great toy for our best boys!
Color: Consuela the Cactus - Large, Size: Large Dog
You can never go wrong with BarkBox toys and this was no exception. Our dogs like toys that have squeakers and that they can tear into. This style of toy fits the bill. The design is cute as well. I’ve had this in the house for months and, while it’s definitely seen better days, it’s still intact and they haven’t gotten to the inner layer. (Not for want of trying.) The perfect type of toy for our fur babies.
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Reviewed in the United States on February 10, 2026
A
Verified Purchase
Amazon Customer
Birmingham, US
★★★★★ 5
Survives 7 months so far.
Color: Christmas Consuela, Size: Large Dog
It is still intact after nearly 7 months of constant play. My blue heeler normally destroys toys in just a few weeks. Consuela has exceeded expectations of survival with an extremely chewy, destruction prone dog.
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Reviewed in the United States on June 6, 2026

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